The study of the networks of protein-protein interactions within a cell, called “interactome”, provides information about the organization of the cell and allows us to identify proteins and signaling pathways that are disrupted or deregulated during a disease condition.
In this course, through a practical example, we will use the open-source software Cytoscape and some of its apps to extract protein-protein interaction data, build the network, visualize and explore it in order to detect topological properties, find potential topological clusters and perform functional network enrichment analysis.
December 10th, 2024 | ||
Time | Learning Experience | Topic |
09:00-10:00 | Lecture | Introduction to Protein-Protein Interactions (PPIs) and Molecular Interaction Resources |
10:00-10:30 | Lecture | Brief introduction to network biology and Cytoscape |
10:30-10:45 | Break | |
10:45-13:00 | Exercise | Building a molecular interaction network and analysing its topological features via Cytoscape |
• Deadline for applications (via the YMW registration form): 30th November 2024
• Chosen participants will be notified by: 3rd December 2024
• Course date: 10th December 2024
Venue
This is an online course
Fee
The course does not include a fee
Registration
The application for participating to the training course is closed.
Selection procedure
A maximum of 30 candidates will be selected on a first-come- first-served basis. Selected participants will be notified by 3rd December 2024.
Prof. Luana Licata – University of Rome “Tor Vergata”, ELIXIR-IT, Italy
Prof. Anna Marabotti, University of Salerno, ELIXIR-IT, Italy
Luana Licata, University of Rome “Tor Vergata”, ELIXIR-IT, Italy
Alessia Pinto, PhD student, University of Rome “Tor Vergata”, ELIXIR-IT, Italy
Francesco Gregoris, University of Padua, Italy
For all kinds of queries, please contact the organiser Anna Marabotti at: amarabotti@unisa.it or please write to elixir.ita.training@gmail.com